David Villa makes his 100th MLS appearance for NYCFC in the 2018 Home Opener vs. LA Galaxy.
El Guaje will look to add to his 65 goals for the Club when Sigi Schmid's men come to town for the first Bronx battle of the year.
Elsewhere, new signing from USL Affiliate San Antonio Sebastien Ibeagha makes his first start for the Club, coming in to replace Maxime Chanot who is suspended.
The Luxembourg international defender sits out for one game following his late red card in the 2-0 season-opening win over Sporting KC last weekend.
That's the only change to the XI, meaning Anton Tinnerholm and Jesus Medina make their home debuts for the Boys in Blue.
Villa sits at the apex of the XI, with Medina and Wallace on either side, backed up by Maxi Moralez, Yangel Herrera and Alex Ring.
In defense, Ben Sweat keeps his place at left-back ahead of Ronald Matarrita, while Alexander Callens partners Ibeagha to the left of Tinnerholm, who plays at right-back.
Sean Johnson will be looking to make it 180' without conceding a goal in 2018 on what promises to be a special opening night at Yankee Stadium.
You can watch the game on YES Network, with Spanish commentary available via SAP. Radio broadcasts are available in English on WNYE 91.5 FM and in Spanish on WADO 1280.
NYCFC XI: Johnson, Tinnerholm, Callens, Ibeagha, Sweat, Ring, Herrera, Moralez, Medina, Wallace, Villa (C)
SUBS: Stuver, Matarrita, Abdul-Salaam, Hountondji, Awuah, Ofori, McNamara, Tajouri-Shradi